Red Hot Mamas Menopause Education and Support Programs
Published: April 24, 2026
- Low-dose antidepressants — Serotonin reuptake inhibitors (SSRIs) and serotonin and norepinephrine reuptake inhibitors (SNRIs) are effective nonhormonal treatments for hot flashes. The SSRI paroxetine (Brisdelle) is the first nonhormonal prescription treatment approved for treating hot flashes. Other SSRIs like escitalopram (Lexapro) and citalopram (Celexa), and SNRIs like venlafaxine (Effexor XL) and desvenlafaxine (Pristiq) are used for hot flashes.
- Gabapentin (Neurontin) — a medication that prevents seizures has also been effective in treating hot flashes.
- Pregabalin (Lyrica) — a medication used to treat nerve-related pain seems to be effective in treating hot flashes.
- Clonidine (Catapres) — a medication to treat high blood pressure is sometimes used to treat hot flashes but it has unpleasant side effects.
- Newer options — like fezolinetant (Veozah) and elinzanetant (Lynkuet) are used to treat hot flashes and night sweats associated with menopause. These non-hormonal prescribed medications block a receptor in the brain that causes hot flashes.
Lynkuet (elinzanetant): In addition to treating hot flashes and night sweats, Lynkuet has also been shown to improve sleep disturbances in menopausal women, independent of its effects on hot flashes.
Stellate Ganglion Block
Is a procedure (treatment) used for pain which involves an injection of anesthetic into the sympathetic nerves in the front of the neck. This procedure has shown promise as a treatment for hot flashes.
